Female

Although the traditional melodramas portrayed most villains as mustache-bearing males, the idea of evil, misguided or just plain confusing female villains has been around since time began.

Ranging from wicked witches and stepmothers to seductive sirens to militant man-haters, female villains are just as capable of sowing misery as their male counterparts.

Please note that, no matter what the universe the female villain is from says, robots or mechanically/artificially created entities with feminine programming do not count and are to be labeled as Genderless.